Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.76 |
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588313 | 0.89 | NOX1 (0.74) | NOX1SMPD3MAPTTP53THRB | |
| SCHEMBL175592 | 0.89 | SMPD3 (0.75) | NOX1SMPD3MAPTTP53ALOX5 | |
| SCHEMBL9425243 | 0.88 | NOX1 (0.58) | NOX1SMPD3CYP1A1CYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL9648176 | 0.88 | SMPD3 (0.73) | NOX1SMPD3MAPTTP53ALOX5 | |
| SCHEMBL10702951 | 0.87 | MAPT (0.61) | NOX1SMPD3MAPTTP53ALOX5 | |
| Hydrochloric Acid SCHEMBL9426019 | 0.87 | NOX1 (0.57) | NOX1SMPD3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6465442 | 0.86 | NOX1 (0.81) | NOX1SMPD3MAPTTP53ALOX5 | |
| SCHEMBL6466417 | 0.85 | NOX1 (0.79) | NOX1SMPD3MAPTTP53THRB | |
| SCHEMBL9425683 | 0.85 | SMPD3 (0.82) | NOX1SMPD3MAPTTP53THRB | |
| SCHEMBL11613918 | 0.84 | MAPT (0.64) | NOX1SMPD3MAPTTP53ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347139-A2 | Imidazole leuco dye composition containing 4'-hydroxyacetanilide diagnostic kit and method using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-12-20 | — | — | EP | claimed |
| US-4089747-A | OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| EP-0887427-B1 | Amplification and detection of hiv-1 and/or hiv-2 | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2006-01-11 | — | — | EP | disclosed |
| US-6936415-B1 | Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more DNA's using primers having matched melting temperatures | CUMMINS THOMAS J (US) | 2005-08-30 | — | — | US | disclosed |
| EP-0707077-B1 | Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-0684316-B1 | Homogeneous method for assay of double-stranded nucleic acids using fluorescent dyes and kit useful therein | JOHNSON & JOHNSON CLIN DIAG (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0702090-B1 | Coamplification of target nucleic acids using volume exclusion agent, in reaction composition, test kit and test device useful therefor | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6709813-B1 | POLYMERASE CHAIN REACTION (PCR) USING TEST KITS AND BUFFERED COMPOSITIONS CONTAINING ?MATCHED? PRIMERS FOR ONE OR MORE TARGET NUCLEIC ACIDS, ONE OF WHICH IS HUMAN CYTOMEGALOVIRUS DNA | ORTHO-CLINICAL DIAGNOSTICS, INC. | 2004-03-23 | — | — | US | disclosed |
| EP-0747704-B1 | Immunoassay element containing a diaryl telluride compound to increase its stability | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0903583-B1 | Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0795751-B1 | Whole blood sample preparation for polymerase chain reaction using ammonium chloride and a carboxylic acid or metal carboxylate for selective red blood cell lysis | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2003-09-17 | — | — | EP | disclosed |
| US-4788140-A | OPTICAL DENSITY, FILTER DYE | EASTMAN KODAK COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0116307-B1 | COMPOSITION, ANALYTICAL ELEMENT AND METHOD FOR THE QUANTIFICATION OF CREATINE KINASE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4713327-A | SUPPORT, REGISTRATION, AND ISOTROPIC POROUS SPREADING LAYER | EASTMAN KODAK COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0239222-A1 | Analytical element containing photosensitive compound and filter layer and method of use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0200541-A2 | Immunochemical method and analytical composition and element for determination of creatine kinase-MB | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0200540-A2 | Analytical element and method for determination of creatine kinase isoenzyme | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4547461-A | MEASUREMENT OF OPTICAL DENSITY CHANGE | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0116307-A2 | Composition, analytical element and method for the quantification of creatine kinase | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-08-22 | — | — | EP | disclosed |
| US-4089747-A | OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | disclosed |