Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313680 | 0.71 | — | — | |
| SCHEMBL7011872 | 0.71 | KEAP1 (0.52) | FFAR1KEAP1P4HTMTBXAS1HCAR2 | |
| SCHEMBL1648472 | 0.71 | KDM4E (0.45) | FFAR1P4HTMTBXAS1HCAR2 | |
| SCHEMBL2113281 | 0.70 | FFAR1 (0.53) | FFAR1KEAP1P4HTMTBXAS1NPSR1 | |
| SCHEMBL25660463 | 0.69 | CYP1A2 (0.53) | FFAR1KEAP1TBXAS1 | |
| SCHEMBL31080880 | 0.69 | CYP1A2 (0.53) | FFAR1KEAP1TBXAS1 | |
| SCHEMBL18534282 | 0.68 | FFAR1 (0.37) | FFAR1KEAP1P4HTMTBXAS1NPSR1 | |
| SCHEMBL29921453 | 0.65 | KEAP1 (0.41) | FFAR1KEAP1P4HTMTBXAS1NPSR1 | |
| SCHEMBL18906036 | 0.65 | FFAR1 (0.49) | FFAR1KEAP1P4HTMTBXAS1 | |
| SCHEMBL2884150 | 0.65 | FFAR1 (0.68) | FFAR1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424368-A1 | PYRROLOTRIAZINE COMPOUNDS | Locus Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | claimed |
| CN-115605605-A | Engineered macromolecules for nanoelectronic measurements | 通用测序技术公司（US） | 2023-01-13 | — | — | CN | disclosed |
| EP-4097242-A1 | MACROMOLECULES ENGINEERED FORNANOELECTRONIC MEASUREMENT | Universal Sequencing Technology Corporation (US) | 2022-12-07 | — | — | EP | disclosed |
| EP-2424368-A1 | PYRROLOTRIAZINE COMPOUNDS | Locus Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |