Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706670 | 0.84 | NOTUM (0.41) | NOTUMIDO1PSDGSK3BMAOA | |
| SCHEMBL10156475 | 0.81 | PSD (0.41) | NOTUMIDO1PSDMAOAMAOB | |
| SCHEMBL1708378 | 0.76 | PSD (0.41) | NOTUMIDO1PSDMAOAMAOB | |
| SCHEMBL11169710 | 0.71 | MEN1 (0.73) | IDO1MCL1LMNAMAPTHTT | |
| SCHEMBL4446050 | 0.70 | MAOA (0.64) | GSK3BMAOAMAOBMCL1LMNA | |
| SCHEMBL25364606 | 0.70 | ERBB2 (0.45) | PSDGSK3BMAOAMAOBMAP2 | |
| SCHEMBL72752 | 0.68 | — | — | |
| Water SCHEMBL27942269 | 0.68 | MAOA (0.73) | GSK3BMAOAMAOBCNR1LMNA | |
| SCHEMBL8217056 | 0.67 | NOTUM (0.43) | NOTUMIDO1MAOBKMT2AMEN1 | |
| SCHEMBL20160990 | 0.66 | MAOB (0.50) | IDO1PSDGSK3BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094705-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-04-18 | — | — | EP | disclosed |