SCHEMBL1756078

SCHEMBL1756078

S[C@@H]1CCCC[C@@H]1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11640981 1.00
SCHEMBL15781544 1.00
SCHEMBL11640986 1.00
SCHEMBL64268 1.00
SCHEMBL1756079 1.00
SCHEMBL10980272 0.95
SCHEMBL22901407 0.95 ALDH1A1 (0.36)
SCHEMBL14674612 0.95
SCHEMBL14674108 0.95 ALDH1A1 (0.36)
SCHEMBL14674107 0.95 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216521-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES IMMUNOGEN INC (US) 2024-07-04 US disclosed
US-20240216521-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES IMMUNOGEN INC (US) 2024-07-04 US disclosed
US-11833214-B2 Methods of preparing cell-binding agent-drug conjugates IMMUNOGEN, INC. (US) 2023-12-05 US disclosed
US-11833214-B2 Methods of preparing cell-binding agent-drug conjugates IMMUNOGEN, INC. (US) 2023-12-05 US disclosed
US-20200405874-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES IMMUNOGEN, INC. 2020-12-31 US disclosed
US-8507654-B2 Altered antibodies UCB PHARMA S.A. (BE) 2013-08-13 US disclosed
US-8507654-B2 Altered antibodies UCB PHARMA S.A. (BE) 2013-08-13 US disclosed
US-8378073-B2 Process for attaching effector molecules to proteins UCB PHARMA S.A. (BE) 2013-02-19 US disclosed
US-8378073-B2 Process for attaching effector molecules to proteins UCB PHARMA S.A. (BE) 2013-02-19 US disclosed
EP-2074143-B1 ALTERED ANTIBODIES UCB PHARMA SA (BE) 2012-04-18 EP disclosed
EP-1912673-B1 PROCESS FOR ATTACHING EFFECTOR MOLECULES TO PROTEINS UCB PHARMA SA (BE) 2011-03-23 EP disclosed
US-20100093977-A1 Altered Antibodies UCB PHARMA S.A. (BE) 2010-04-15 US disclosed
US-20100093977-A1 Altered Antibodies UCB PHARMA S.A. (BE) 2010-04-15 US disclosed
US-20080306246-A1 Process for Attaching Effector Molecules to Proteins UCB PHARMA S.A. (BE) 2008-12-11 US disclosed
US-20080306246-A1 Process for Attaching Effector Molecules to Proteins UCB PHARMA S.A. (BE) 2008-12-11 US disclosed
WO-2008038024-A1 ALTERED ANTIBODIES UCB PHARMA S.A. (BE) 2008-04-03 WO disclosed
WO-2007003898-A1 PROCESS FOR ATTACHING EFFECTOR MOLECULES TO PROTEINS UCB PHARMA S.A. (BE) 2007-01-11 WO disclosed
EP-0372870-A2 Novel heterocyclic pesticidal compounds ROUSSEL-UCLAF (FR) 1990-06-13 EP disclosed