Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | GALR3 | O60755 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17574201 | 1.00 | RECQL (0.74) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19434691 | 0.91 | RECQL (0.71) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL17067806 | 0.91 | RECQL (0.67) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19434693 | 0.91 | RECQL (0.71) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19441401 | 0.90 | RECQL (0.66) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19449614 | 0.88 | RECQL (0.80) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL31043533 | 0.88 | RECQL (0.80) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL17560900 | 0.88 | RECQL (0.80) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19441400 | 0.88 | RECQL (0.63) | RECQLKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19449680 | 0.84 | RECQL (0.66) | RECQLKDM4EKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188722-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | Neoculi Pty Ltd (AU) | 2017-07-12 | — | — | EP | claimed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | claimed |