Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22695385 | 0.97 | NPSR1 (0.32) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL345810 | 0.94 | KDM4E (0.37) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL801440 | 0.94 | KDM4E (0.37) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL801717 | 0.94 | KDM4E (0.37) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9920535 | 0.94 | NPSR1 (0.37) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL801432 | 0.92 | NPSR1 (0.34) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL801102 | 0.92 | NPSR1 (0.34) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11921054 | 0.89 | NPSR1 (0.42) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12879596 | 0.89 | NPSR1 (0.35) | NPSR1KDM4EL3MBTL1ATMLMNA | |
| SCHEMBL801300 | 0.89 | NPSR1 (0.35) | NPSR1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |