Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801432 | 0.97 | NPSR1 (0.34) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL801102 | 0.97 | NPSR1 (0.34) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL801099 | 0.96 | KDM4E (0.42) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL345810 | 0.95 | KDM4E (0.37) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL801717 | 0.95 | KDM4E (0.37) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL801440 | 0.95 | KDM4E (0.37) | NPSR1KDM4EATML3MBTL1MEN1 | |
| SCHEMBL12879596 | 0.94 | NPSR1 (0.35) | NPSR1KDM4EATML3MBTL1LMNA | |
| SCHEMBL801163 | 0.92 | NPSR1 (0.38) | NPSR1KDM4EL3MBTL1MEN1MAPT | |
| SCHEMBL801191 | 0.90 | NPSR1 (0.36) | NPSR1KDM4EL3MBTL1MEN1MAPT | |
| SCHEMBL801194 | 0.90 | PPARG (0.37) | NPSR1KDM4EMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INPP5B, EZH2, PLCB3 | NPSR1 4411/4885KDM4E 1186/4885ATM 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.