Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563460 | 1.00 | ALDH1A1 (0.47) | ALDH1A1EPHX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17563242 | 1.00 | ALDH1A1 (0.47) | ALDH1A1EPHX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2900931 | 0.80 | ALDH1A1 (0.50) | ALDH1A1EPHX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21729626 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6722047 | 0.78 | PSEN1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL20582658 | 0.78 | PSEN1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL18629949 | 0.78 | PSEN1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL17666343 | 0.78 | PSEN1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL1444907 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL19684364 | 0.76 | PSEN1 (0.46) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160068630-A1 | Process for Preparing Polycarbonates by Polymerization of Five-Membered-Ring Cyclic Carbonates | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068630-A1 | Process for Preparing Polycarbonates by Polymerization of Five-Membered-Ring Cyclic Carbonates | CWC15, DKC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 2195/4885EPHX1 785/4885SMN1; SMN2 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.