Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18466735 | 1.00 | KDM4E (0.38) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL17577112 | 1.00 | KDM4E (0.38) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL17563722 | 0.97 | KDM4E (0.40) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL18679867 | 0.86 | KDM4E (0.43) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL17564313 | 0.85 | SMN1; SMN2 (0.36) | KDM4EKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18757519 | 0.85 | KDM4E (0.42) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL17564316 | 0.84 | KDM4E (0.39) | KDM4EKMT2AHTTCA12CA1 | |
| SCHEMBL18466785 | 0.83 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17564312 | 0.83 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17577083 | 0.83 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |