Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18466784 | 0.96 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTGAALMNAALDH1A1 | |
| SCHEMBL17564309 | 0.85 | KDM4E (0.38) | SMN1; SMN2GAALMNAALDH1A1KDM4E | |
| SCHEMBL17577112 | 0.85 | KDM4E (0.38) | SMN1; SMN2GAALMNAALDH1A1KDM4E | |
| SCHEMBL18466735 | 0.85 | KDM4E (0.38) | SMN1; SMN2GAALMNAALDH1A1KDM4E | |
| SCHEMBL18467398 | 0.83 | LMNA (0.46) | MAPTGAALMNAALDH1A1GLA | |
| SCHEMBL17563722 | 0.83 | KDM4E (0.40) | SMN1; SMN2GAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL18757519 | 0.80 | KDM4E (0.42) | SMN1; SMN2MAPTGAALMNAALDH1A1 | |
| SCHEMBL17564357 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTGAALMNAALDH1A1 | |
| SCHEMBL17563721 | 0.76 | LMNA (0.42) | MAPTGAALMNAALDH1A1KDM4E | |
| SCHEMBL18679867 | 0.76 | KDM4E (0.43) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |