Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 17/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756462 | 0.92 | GYS1 (0.58) | GYS1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1756390 | 0.84 | GYS1 (0.82) | GYS1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1756338 | 0.81 | MRGPRX4 (0.62) | GYS1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL1756371 | 0.81 | MRGPRX4 (0.65) | GYS1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1756401 | 0.78 | GYS1 (0.63) | GYS1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1756426 | 0.76 | GYS1 (0.79) | GYS1MAOBMRGPRX4 | |
| SCHEMBL1756438 | 0.75 | GYS1 (1.00) | GYS1 | |
| SCHEMBL1756394 | 0.74 | MRGPRX4 (0.69) | GYS1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL17505888 | 0.73 | GYS1 (0.69) | GYS1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1756340 | 0.72 | MRGPRX4 (0.63) | GYS1NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058154-A1 | BIPHENYL CARBOXYLIC ACIDS AND BIOISOSTERES AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-05-19 | — | — | WO | disclosed |