Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 11/20 | 0.69 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756390 | 0.87 | GYS1 (0.82) | GYS1MRGPRX4KMT2A | |
| SCHEMBL1756379 | 0.87 | GYS1 (0.53) | GYS1MRGPRX4KMT2AFFAR1 | |
| SCHEMBL1756363 | 0.85 | GYS1 (0.81) | GYS1MRGPRX4KMT2AFFAR1PPARD | |
| SCHEMBL1756426 | 0.83 | GYS1 (0.79) | GYS1MRGPRX4 | |
| SCHEMBL1756400 | 0.83 | GYS1 (0.68) | GYS1MRGPRX4FFAR1PPARD | |
| SCHEMBL1756438 | 0.82 | GYS1 (1.00) | GYS1 | |
| SCHEMBL1542780 | 0.79 | GYS1 (0.74) | GYS1MRGPRX4FFAR1PPARD | |
| SCHEMBL2036261 | 0.79 | GYS1 (0.71) | GYS1FFAR1PPARD | |
| SCHEMBL1756401 | 0.74 | GYS1 (0.63) | GYS1KMT2A | |
| SCHEMBL14933712 | 0.73 | GYS1 (1.00) | GYS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058154-A1 | BIPHENYL CARBOXYLIC ACIDS AND BIOISOSTERES AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-05-19 | — | — | WO | disclosed |