SCHEMBL1756475

SCHEMBL1756475

CCCCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(O)[C@H]1OP(=O)(O)O

nearest known ligand 0.88

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.85
▸ CHAT P28329 2/20 0.82
▸ EP300 Q09472 3/20 0.80
▸ KAT5 Q92993 2/20 0.80
▸ AURKA O14965 2/20 0.80
▸ KAT2B Q92831 1/20 0.80
▸ CREBBP Q92793 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366095 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Dodecanoyl-Coa SCHEMBL4309283 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL2934083 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Decanoyl-Coa SCHEMBL24667667 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL1129961 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Octanoyl-Coa SCHEMBL24667663 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL11027446 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Octanoyl-Coa SCHEMBL2370508 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL20970006 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Dodecanoyl-Coa SCHEMBL187868 1.00 NAA50 (0.85) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980473-A Organisms producing less crotonic acid 环球生物能源公司 2024-05-03 — — CN claimed
CN-116157518-A Pichia pastoris mutant strain with improved sphingolipid and sphingoid base productivity and preparation method thereof 索路思生物技术有限公司 2023-05-23 — — CN claimed
CN-119857063-A Composition, ceramide liposome freeze-dried powder, and preparation method and application thereof 深圳瑞德林生物技术有限公司 2025-04-22 — — CN disclosed
CN-119630646-A TEAD targeting compounds and methods thereof 新加坡科技研究局 2025-03-14 — — CN disclosed
CN-119541901-A Drug permeability clinical prediction model, construction method thereof and nonspecific drug permeability evaluation method 北京大学第一医院(北京大学第一临床医学院) 2025-02-28 — — CN disclosed
CN-119405642-A Application of rhodotorula erythrosin in preparation of product for effectively preventing/treating hypercholesteremia 江南大学 2025-02-11 — — CN disclosed
WO-2024197185-A1 METHODS AND COMPOSITIONS FOR DISSECTING ORGANELLE PHYSIOLOGY THE BROAD INSTITUTE, INC. (US) 2024-09-26 — — WO disclosed
CN-118339307-A Biosynthetic preparation of vitamin A compounds 康纳根有限公司 2024-07-12 — — CN disclosed
CN-112771169-B Method for recovering water-immiscible isoprenoid compounds from microbial biomass 阿迈瑞斯公司 2024-07-09 — — CN disclosed
CN-118021974-A Application of palmitoylation of Cys113 and Cys274 sites of MyD88 protein in treatment of non-alcoholic fatty liver disease 重庆医科大学 2024-05-14 — — CN disclosed
CN-117980473-A Organisms producing less crotonic acid 环球生物能源公司 2024-05-03 — — CN disclosed
WO-2001062744-A2 SUBSTITUTED PIPERAZINE COMPOUNDS CV THERAPEUTICS, INC. (US) 2001-08-30 — — WO disclosed
WO-2001062711-A2 SUBSTITUTED ALKYLENE DIAMINE COMPOUNDS CV THERAPEUTICS, INC. (US) 2001-08-30 — — WO disclosed
WO-2001062749-A1 SUBSTITUTED PIPERAZINE COMPOUNDS CV THERAPEUTICS, INC. (US) 2001-08-30 — — WO disclosed
WO-2000070017-A2 METHODS USING OF FAB I AND COMPOUNDS MODULATING FAB I ACTIVITY SMITHKLINE BEECHAM CORPORATION (US) 2000-11-23 — — WO disclosed
EP-0932387-A1 SKIN CARE COMPOSITIONS CONTAINING COMBINATIONS OF COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 1999-08-04 — — EP disclosed
EP-0872244-A1 Cosmetic or pharmaceutical composition containing an Andiroba extract LABORATOIRES DE BIOLOGIE VEGETALE YVES ROCHER (FR) 1998-10-21 — — EP disclosed
US-5759556-A Skin care compositions containing certain cyclic aliphatic unsaturated compounds and retinol or retinyl ester CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-06-02 — — US disclosed
WO-1998013020-A1 SKIN CARE COMPOSITIONS CONTAINING COMBINATIONS OF COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 1998-04-02 — — WO disclosed
EP-0243167-B1 A NOVEL MICROORGANISM, A NOVEL ESTERASE AND METHOD FOR PREPARING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-19 — — EP disclosed
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