SCHEMBL1756519

SCHEMBL1756519

C=C(C)C(=O)OCCOC(=O)C(=C)CC

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.64
TSHR P16473 5/20 0.57
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 3/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26811663 0.92 THRB (0.56) THRBTSHRALDH1A1TDP1POLB
SCHEMBL19998251 0.92 TSHR (0.59) THRBTSHRALDH1A1TDP1POLB
SCHEMBL11166867 0.92 TSHR (0.63) THRBTSHRALDH1A1TDP1POLB
SCHEMBL57345 0.91 THRB (0.50) THRBTSHRALDH1A1TDP1HSD17B10
SCHEMBL18823247 0.90 TSHR (0.72) THRBTSHRALDH1A1TDP1POLB
SCHEMBL18822940 0.90 TSHR (0.72) THRBTSHRALDH1A1TDP1POLB
SCHEMBL18823318 0.90 TSHR (0.72) THRBTSHRALDH1A1TDP1POLB
SCHEMBL18823426 0.90 TSHR (0.72) THRBTSHRALDH1A1TDP1POLB
SCHEMBL21611811 0.87 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
Propane SCHEMBL11405097 0.86 THRB (0.75) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040117007-A1 Medicated stent having multi-layer polymer coating STS BIOPOLYMERS, INC. (US) 2004-06-17 US claimed
US-8927493-B2 Promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue KRINGLE PHARMA, INC. (JP) 2015-01-06 US disclosed
US-8287590-B2 Medicated stent having multi-layer polymer coating ANGIOTECH BIOCOATINGS CORP. 2012-10-16 US disclosed
US-20110312887-A1 PROMOTER FOR REGENERATION OF TENDON-BONE JUNCTION TISSUE OR LIGAMENT-BONE JUNCTION TISSUE KRINGLE PHARMA, INC. (JP) 2011-12-22 US disclosed
US-7943353-B2 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-05-17 US disclosed
US-20100331967-A1 MEDICATED STENT HAVING MULTI-LAYER POLYMER COATING ANGIOTECH BIOCOATINGS CORP. (US) 2010-12-30 US disclosed
US-7771468-B2 Medicated stent having multi-layer polymer coating ANGIOTECH BIOCOATINGS CORP. (US) 2010-08-10 US disclosed
US-20090286278-A1 MULTI-LAYER CELL ENCAPSULATION FOR TISSUE ENGINEERING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-11-19 US disclosed
EP-1680047-A1 MEDICATED STENT HAVING MULTI-LAYER POLYMER COATING Angiotech BioCoatings, Corp. (US) 2006-07-19 EP disclosed
US-20050220891-A1 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-10-06 US disclosed
EP-0822824-A4 METHOD OF PRETREATING VIABLE TISSUE OR CELLS TO BE CONTAINED WITHIN A SEMIPERMEABLE VESSEL UNIV EMORY (US) 2003-03-05 EP disclosed
US-5795570-A TISSUES OR CELLS AND MEMBRANES EMORY UNIVERSITY (US) 1998-08-18 US disclosed
EP-0822824-A1 METHOD OF PRETREATING VIABLE TISSUE OR CELLS TO BE CONTAINED WITHIN A SEMIPERMEABLE VESSEL EMORY UNIVERSITY (US) 1998-02-11 EP disclosed
US-5663039-A AT LEAST A PORTION OF THE SURFACE IS COVERED WITH AN ADDITIVE SELECTED FROM THE GROUP CONSISTING OF A SULFITE, A HYDROXYLAMINE OR A BENZOIC OR SULFONIC ACID COMPOUND KONICA CORPORATION (JP) 1997-09-02 US disclosed
EP-0583244-B1 METHOD OF PRODUCING ZERO-ORDER CONTROLLED-RELEASE DEVICES SOUTHERN RES INST (US) 1997-01-08 EP disclosed
WO-1996031223-A1 METHOD OF PRETREATING VIABLE TISSUE OR CELLS TO BE CONTAINED WITHIN A SEMIPERMEABLE VESSEL EMORY UNIVERSITY (US) 1996-10-10 WO disclosed
EP-0678781-A1 Solid processing agent for silver halide photographic light-sensitive materials KONICA CORPORATION (JP) 1995-10-25 EP disclosed
WO-1995015343-A1 POLY-β-1→4-N-ACETYLGLUCOSAMINE MARINE POLYMER TECHNOLOGIES, INC. (US) 1995-06-08 WO disclosed
US-5085866-A Method of producing zero-order controlled-released devices SOUTHERN RESEARCH INSTITUTE (US) 1992-02-04 US disclosed
US-4887097-A INK RECEIVER IS BLEND OF WATER ABSORBING RESINS CANON KABUSHIKI KAISHA (JP) 1989-12-12 US disclosed