SCHEMBL1756546

SCHEMBL1756546

CCCCCc1ccccc1S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.55
TLR8 Q9NR97 1/20 0.46
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
NR1H2 P55055 1/20 0.45
NR1H3 Q13133 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
CYSLTR2 Q9NS75 6/20 0.44
CYSLTR1 Q9Y271 6/20 0.44
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28134408 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL30118162 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL29478084 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL11353366 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL28981353 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL2557787 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL3348597 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL786162 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL2552510 0.98 LIPG (0.58) LIPGTLR8THRATHRBNR1H2
SCHEMBL27882373 0.98 LIPG (0.53) LIPGTLR8THRATHRBNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644581-B Amino acid containing aryl thiophenol or aryl selenol modified, recombinant protein, and biosynthesis method and application thereof 北京惠大生物科技有限公司 2024-07-16 CN claimed
CN-117903024-B Synthesis method of aryl thiophenol derivative 浙江扬帆新材料股份有限公司 2024-07-16 CN claimed
CN-117903024-A Synthesis method of aryl thiophenol derivative 浙江扬帆新材料股份有限公司 2024-04-19 CN claimed
CN-117383993-A Direct cross coupling method of aryl thiophenol and aryl bromide 南京工业大学 2024-01-12 CN claimed
CN-116947719-A Synthesis method of visible light two-dimensional alkene nanomaterial synergistic catalysis disulfide compound 南通大学 2023-10-27 CN claimed
CN-114539107-B Aromatic sulfonyl modified difluoromethyl reaction building block and synthesis method thereof 平顶山学院 2023-09-15 CN claimed
CN-116218615-A Cleaning compositions and methods of use thereof 富士胶片电子材料美国有限公司 2023-06-06 CN claimed
CN-111454296-B Palladium complex containing meta-carborane triazole ligand and preparation method and application thereof 上海应用技术大学 2023-04-28 CN claimed
CN-114634432-B High-efficiency synthesis method of alkyl aryl thioether compound 润药仁智(北京)科技有限公司 2023-03-14 CN claimed
CN-115724882-A Synthesis method of thiophosphate compound 南通大学 2023-03-03 CN claimed
WO-2005103027-A1 SYNTHESISING METHOD AND BENZOXATHIEPINE INTERMEDIATES PIERRE FABRE MEDICAMENT (FR) 2005-11-03 WO claimed
CN-1245165-A Process for preparing s-aryl-semi-cystine and its derivatives HOFFMANN LA ROCHE (CH) 2000-02-23 CN claimed
WO-1996023749-A1 CHEMICAL LIBRARIES, LABELLING AND DECONVOLUTION THEREOF ZENECA LIMITED (GB) 1996-08-08 WO claimed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US claimed
US-5283016-A Method for preparing photosensitive microcapsules THE MEAD CORPORATION (US) 1994-02-01 US claimed
EP-0271307-B1 METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS HOECHST CELANESE CORPORATION (US) 1992-01-02 EP claimed
US-4794205-A Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-12-27 US claimed
EP-0271307-A2 Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-06-15 EP claimed
EP-0269434-A1 Method for producing aminothiophenols and their derivatives HOECHST CELANESE CORPORATION (US) 1988-06-01 EP claimed
CN-85101403-A The carbonylation method improvement 1987-01-17 CN claimed