SCHEMBL17570204

SCHEMBL17570204

c1ccc(-c2nsc(-c3cccc(-c4nc(-c5ccccc5)ns4)c3)n2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.66
HSD17B2 P37059 2/20 0.66
CYP19A1 P11511 5/20 0.55
ADORA3 P0DMS8 4/20 0.55
MAPT P10636 2/20 0.55
ADORA2A P29274 2/20 0.55
ADORA2B P29275 2/20 0.55
ADORA1 P30542 2/20 0.55
SNCA P37840 1/20 0.53
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570194 0.92 HSD17B1 (0.66) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL2212694 0.90 CYP19A1 (0.67) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL19196280 0.89 HSD17B1 (0.62) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL28393143 0.88 HSD17B1 (0.57) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL17640610 0.86 CYP19A1 (0.66) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL28393178 0.85 HSD17B1 (0.58) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL28402665 0.84 HSD17B1 (0.53) HSD17B1HSD17B2CYP19A1MAPTADORA2A
SCHEMBL30287350 0.84 CYP19A1 (0.73) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL28406603 0.84 CYP19A1 (0.73) HSD17B1HSD17B2CYP19A1ADORA3MAPT
SCHEMBL21915702 0.82 HSD17B1 (0.55) HSD17B1HSD17B2CYP19A1ADORA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed