SCHEMBL17570211

SCHEMBL17570211

O=C(c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)cc1)c1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.57
PNLIP P16233 2/20 0.53
LIG1 P18858 1/20 0.49
NR4A1 P22736 1/20 0.47
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HTT P42858 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 2/20 0.46
MMP2 P08253 2/20 0.45
MMP9 P14780 2/20 0.45
APEX1 P27695 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17559299 0.93 STS (0.64) STSPNLIPLIG1HTTPOLB
SCHEMBL17570185 0.91 STS (0.61) STSPNLIPLIG1ALDH1A1HTT
SCHEMBL19268122 0.89 STS (0.59) STSPNLIPLIG1HTTPOLB
SCHEMBL17570190 0.89 LIG1 (0.64) STSPNLIPLIG1ALDH1A1HTT
SCHEMBL19268119 0.87 HTT (0.60) STSPNLIPLIG1ALDH1A1NPC1
SCHEMBL4339742 0.85 MAPT (0.50) STSNR4A1ALDH1A1HTTPOLB
SCHEMBL11451250 0.85 MAPT (0.50) STSNR4A1ALDH1A1HTTPOLB
SCHEMBL17207952 0.84 HPGD (0.56) ALDH1A1POLBMAPTAPEX1CTDSP1
SCHEMBL809347 0.84 HPGD (0.56) ALDH1A1POLBMAPTAPEX1CTDSP1
SCHEMBL12960261 0.84 HPGD (0.56) ALDH1A1POLBMAPTAPEX1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-23 US disclosed
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-09-03 US disclosed
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-08-24 US disclosed
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-08-24 US disclosed
WO-2016034689-A1 HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10954359-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HSPA1B, HSPH1 STS 3358/4885PNLIP 4226/4885LIG1 1029/4885
US-10400087-B2 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HAO2, UNG STS 3560/4885PNLIP 4286/4885LIG1 765/4885
US-20170240723-A1 Hydroxybenzophenone-based stabilizers and polymers end-capped with the same TYR, HAO2, UNG STS 3560/4885PNLIP 4286/4885LIG1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.