SCHEMBL17570864

SCHEMBL17570864

Cn1c2cnccc2n2c3ccccc3nc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
PDE10A Q9Y233 2/20 0.45
ATM Q13315 2/20 0.44
PDE2A O00408 1/20 0.43
TP53 P04637 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
TOP2A P11388 1/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TLR7 Q9NYK1 1/20 0.38
RAD51 Q06609 1/20 0.38
LCK P06239 1/20 0.38
GSR P00390 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570839 0.94 MEN1 (0.50) MEN1KMT2APDE10AATMPDE2A
SCHEMBL20929588 0.89 MEN1 (0.47) MEN1KMT2APDE10AATMPDE2A
SCHEMBL17849975 0.89 ATM (0.53) MEN1KMT2APDE10AATMPDE2A
SCHEMBL12799837 0.85 ATM (0.53) MEN1KMT2AATMTP53NPC1
SCHEMBL18083287 0.85 SMN1; SMN2 (0.55) MEN1KMT2AATMTP53NPC1
SCHEMBL25708331 0.76 ATM (0.47) MEN1KMT2AATMPDE2ATP53
SCHEMBL22380560 0.75 MEN1 (0.39) MEN1KMT2APDE10AATMPDE2A
SCHEMBL22380521 0.75 MEN1 (0.39) MEN1KMT2APDE10AATMPDE2A
SCHEMBL22380482 0.75 MEN1 (0.39) MEN1KMT2APDE10AATMPDE2A
SCHEMBL19486455 0.73 SMN1; SMN2 (0.43) MEN1KMT2AATMTP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968229-B2 Seven-membered ring compounds IDEMITSU KOSAN CO., LTD. (JP) 2021-04-06 US disclosed
US-20190245152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-08-08 US disclosed
EP-2993215-B1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2019-06-19 EP disclosed
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2019-04-25 US disclosed
WO-2017178864-A1 SEVEN-MEMBERED RING COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2017-10-19 WO disclosed
EP-3070144-A1 SEVEN-MEMBERED RING COMPOUNDS Idemitsu Kosan Co., Ltd. (JP) 2016-09-21 EP disclosed
EP-3034506-A1 4-functionalized carbazole derivatives for electronic applications Idemitsu Kosan Co., Ltd (JP) 2016-06-22 EP disclosed
EP-2993215-A1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications Idemitsu Kosan Co., Ltd. (JP) 2016-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119291-A1 SEVEN-MEMBERED RING COMPOUNDS MCM7, XPO7, LUC7L2 MEN1 441/4885KMT2A 3830/4885PDE10A 1999/4885
US-10968229-B2 Seven-membered ring compounds MCM7, XPO7, LUC7L2 MEN1 441/4885KMT2A 3830/4885PDE10A 1999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.