Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849983 | 0.87 | ATM (0.45) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL18083287 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL21101316 | 0.81 | KDM4E (0.37) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17570852 | 0.81 | ATM (0.41) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL12799837 | 0.79 | ATM (0.53) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL25708331 | 0.73 | ATM (0.47) | SMN1; SMN2ATMKDM4EMEN1KMT2A | |
| SCHEMBL17570864 | 0.73 | MEN1 (0.50) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL17570839 | 0.73 | MEN1 (0.50) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL26168128 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2ATMKDM4EMAPTMEN1 | |
| SCHEMBL22380184 | 0.72 | BRD4 (0.38) | SMN1; SMN2ATMKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968229-B2 | Seven-membered ring compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20190245152-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2019-08-08 | — | — | US | disclosed |
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| WO-2017178864-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | MCM7, XPO7, LUC7L2 | SMN1; SMN2 3354/4885ATM 4103/4885KDM4E 2621/4885 |
| US-10968229-B2 | Seven-membered ring compounds | MCM7, XPO7, LUC7L2 | SMN1; SMN2 3354/4885ATM 4103/4885KDM4E 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.