Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567898 | 0.80 | CCNC (0.34) | CCNCCDK8 | |
| SCHEMBL19656322 | 0.76 | — | — | |
| SCHEMBL1563913 | 0.75 | ALDH1A1 (0.38) | CCNCCDK8 | |
| SCHEMBL21392315 | 0.72 | EGFR (0.32) | — | |
| SCHEMBL26122121 | 0.72 | EGFR (0.32) | — | |
| SCHEMBL30556857 | 0.72 | EGFR (0.32) | — | |
| SCHEMBL29923236 | 0.71 | CCNC (0.33) | CCNCCDK8 | |
| SCHEMBL30959346 | 0.71 | ERN1 (0.38) | CCNCCDK8 | |
| SCHEMBL30702047 | 0.71 | CA1 (0.31) | CCNCCDK8 | |
| SCHEMBL6118301 | 0.71 | ERN1 (0.38) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993169-A1 | ARYL-PYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | Novartis AG (CH) | 2016-03-09 | — | — | EP | disclosed |