Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 4/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963804 | 0.86 | TSHR (0.40) | CLCN2TTRNR4A1PTGS2MEN1 | |
| SCHEMBL23703865 | 0.85 | HAAO (0.39) | CLCN2NR4A1HAAOADRA2ATSHR | |
| SCHEMBL2258690 | 0.83 | HAAO (0.40) | HAAOMCL1ALDH1A1MYCCYP1A2 | |
| SCHEMBL23089645 | 0.81 | PTGS2 (0.46) | PTGS2KMT2AMETTL3TSHRCASP1 | |
| SCHEMBL28122101 | 0.80 | HAAO (0.38) | AKR1C3KMT2AHAAOMCL1ALDH1A1 | |
| SCHEMBL8127076 | 0.79 | CYP3A4 (0.38) | CLCN2TTRNR4A1PTGS2MEN1 | |
| SCHEMBL23706127 | 0.79 | CSNK2A2 (0.42) | CLCN2TTRNR4A1PTGS2MEN1 | |
| SCHEMBL9592737 | 0.78 | NR1H4 (0.35) | CLCN2NR4A1MEN1AKR1C2KMT2A | |
| SCHEMBL18280372 | 0.78 | HAAO (0.39) | PTGS2MEN1AKR1B10ABCB11CHRM1 | |
| SCHEMBL109811 | 0.77 | CLCN2 (0.49) | CLCN2TTRNR4A1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943760-B2 | Non-nucleotide composition for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100197913-A1 | NON-NUCLEOTIDE COMPOSITION FOR INHIBITING PLATELET AGGREGATION | PLOURDE JR ROBERT | 2010-08-05 | — | — | US | disclosed |
| US-7749981-B2 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-7592445-B2 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1943261-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | Inspire Pharmaceuticals, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| US-20080103304-A1 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | PLOURDE ROBERT JR | 2008-05-01 | — | — | US | disclosed |
| US-7335648-B2 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| EP-1883637-A2 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | Inspire Pharmaceuticals, Inc. (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007056217-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006119507-A2 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060121086-A1 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103304-A1 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | P2RY12, P2RY11, P2RY13 | CLCN2 2165/4885TTR 2424/4885NR4A1 1353/4885 |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | CLCN2 2374/4885TTR 2276/4885NR4A1 1303/4885 |
| US-20100197913-A1 | NON-NUCLEOTIDE COMPOSITION FOR INHIBITING PLATELET AGGREGATION | P2RY12, P2RY13, P2RY11 | CLCN2 2060/4885TTR 2463/4885NR4A1 1578/4885 |
| US-20060121086-A1 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | P2RY12, P2RY11, P2RY13 | CLCN2 1352/4885TTR 4369/4885NR4A1 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.