Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684210 | 0.84 | ADORA2A (0.36) | ADORA2ATLR7ADORA2BADORA1 | |
| SCHEMBL27684232 | 0.82 | ADORA2A (0.53) | ADORA2AADORA2BADORA1 | |
| SCHEMBL27664616 | 0.82 | TLR8 (0.44) | TLR8ADORA2ATLR7ALDH1A1 | |
| SCHEMBL27684253 | 0.80 | PI4KA (0.38) | ADORA2AADORA2BADORA1 | |
| SCHEMBL27664613 | 0.79 | HSP90B1 (0.37) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6269098 | 0.77 | LMNA (0.52) | TLR7ALDH1A1 | |
| SCHEMBL20848047 | 0.76 | ADORA2A (0.52) | TLR8ADORA2AKDRALDH1A1ADORA2B | |
| SCHEMBL27684254 | 0.75 | TLR7 (0.50) | ADORA2ATLR7ADORA2BADORA1 | |
| SCHEMBL3474371 | 0.75 | KDR (0.52) | TLR8ADORA2AKDRALDH1A1ADORA2B | |
| SCHEMBL27684236 | 0.73 | IRAK4 (0.42) | ADORA2AKDRADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284318-B2 | Protein kinase inhibitors | PHARMASCIENCE, INC. (CA) | 2016-03-15 | — | — | US | disclosed |