Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844967 | 0.83 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL11929778 | 0.81 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL1927692 | 0.81 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL6844970 | 0.81 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL11905237 | 0.80 | CTSB (0.34) | CTSB | |
| SCHEMBL12470807 | 0.80 | CTSB (0.34) | CTSB | |
| SCHEMBL1926348 | 0.78 | CTSB (0.45) | CTSBCTSS | |
| SCHEMBL6844968 | 0.78 | CTSB (0.45) | CTSBCTSS | |
| SCHEMBL11929776 | 0.73 | CTSB (0.44) | CTSBCTSS | |
| SCHEMBL13502724 | 0.72 | CTSB (0.39) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284307-B2 | Macrocyclic serine protease inhibitors | IDENIX PHARMACEUTICALS LLC (US) | 2016-03-15 | — | — | US | disclosed |