Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369805 | 0.89 | CHRM2 (0.40) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL3322128 | 0.85 | CHRM2 (0.39) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL5153017 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL1924787 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL376697 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL6491588 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL77478 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL5203966 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL142226 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 | |
| SCHEMBL3949211 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160067302-A1 | Hepatitis C Virus Inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160067302-A1 | Hepatitis C Virus Inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160067302-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, CTRB1 | CHRM2 4009/4885CHRM1 3345/4885CHRM3 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.