SCHEMBL17577477

SCHEMBL17577477

O=C=Nc1ccc(C(=O)c2cccc(N=C=O)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
MAPK1 P28482 1/20 0.42
PBRM1 Q86U86 1/20 0.41
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
PLCG1 P19174 1/20 0.40
TRPA1 O75762 1/20 0.40
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1046632 0.93 TDP1 (0.48) TDP1L3MBTL1ATMMAPK1PBRM1
SCHEMBL9717935 0.91 ATM (0.59) TDP1L3MBTL1ATMMAPK1PBRM1
SCHEMBL22966339 0.91 POLB (0.44) TDP1L3MBTL1ATMPOLBSRD5A2
SCHEMBL22966353 0.87 POLB (0.47) TDP1L3MBTL1ATMMEN1NPC1
SCHEMBL145056 0.85 ALDH1A1 (0.56) TDP1L3MBTL1ATMCYP3A4ALDH1A1
SCHEMBL308386 0.85 CYP3A4 (0.52) TDP1MAPK1CYP3A4ALDH1A1TSHR
SCHEMBL11463962 0.83 TDP1 (0.40) TDP1L3MBTL1ATMMAPK1PBRM1
SCHEMBL17576537 0.82 STS (0.42) TDP1L3MBTL1ATMMAPK1PBRM1
SCHEMBL9778379 0.82 MAPT (0.38) TDP1L3MBTL1ATMMAPK1CYP3A4
SCHEMBL4393821 0.80 MAPT (0.54) TDP1L3MBTL1ALDH1A1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed
US-20210038474-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INCORPORATED 2021-02-11 US disclosed
US-20160282770-A1 MEANDER CONTROL MEMBER, TRANSFER BELT, TRANSFER UNIT, AND IMAGE-FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2016-09-29 US disclosed
US-20160070210-A1 ENDLESS BELT, TRANSFER UNIT, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2016-03-10 US disclosed