⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674423 | 0.85 | — | — | |
| SCHEMBL21202664 | 0.85 | — | — | |
| SCHEMBL10005827 | 0.85 | — | — | |
| SCHEMBL1643472 | 0.85 | — | — | |
| SCHEMBL17577468 | 0.84 | — | — | |
| SCHEMBL12667459 | 0.81 | — | — | |
| SCHEMBL24742859 | 0.81 | — | — | |
| SCHEMBL25485084 | 0.81 | — | — | |
| SCHEMBL10001262 | 0.80 | FGF1 (0.33) | — | |
| SCHEMBL13222901 | 0.80 | FGF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958998-B1 | SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE | SIRNA THERAPEUTICS INC (US) | 2017-12-27 | — | — | EP | disclosed |
| US-20160256570-A1 | SYSTEMIC DELIVERY OF MYOSTATIN SHORT INTERFERING NUCLEIC ACIDS (siNA) CONJUGATED TO A LIPOPHILIC MOIETY | SIRNA THERAPEUTICS, INC. (US) | 2016-09-08 | — | — | US | disclosed |
| US-20160068837-A1 | SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE | SIRNA THERAPEUTICS, INC. (US) | 2016-03-10 | — | — | US | disclosed |