Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 15/20 | 0.38 |
| ▸ | DRD2 | P14416 | 9/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165592 | 0.86 | HRH3 (0.45) | HRH3DRD3 | |
| SCHEMBL165665 | 0.83 | HRH3 (0.43) | HRH3DRD3 | |
| SCHEMBL175170 | 0.82 | NPC1 (0.39) | HRH3DRD3DRD2 | |
| SCHEMBL176068 | 0.76 | HRH3 (0.35) | HRH3 | |
| SCHEMBL165847 | 0.73 | NPC1 (0.38) | HRH3DRD3DRD2 | |
| SCHEMBL166685 | 0.72 | NPC1 (0.37) | HRH3 | |
| SCHEMBL164398 | 0.71 | HRH3 (0.34) | HRH3 | |
| SCHEMBL164792 | 0.70 | NPC1 (0.48) | HRH3 | |
| SCHEMBL15738855 | 0.70 | NPC1 (0.48) | HRH3 | |
| SCHEMBL15738751 | 0.69 | NPC1 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611444-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029070-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |