Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Etidronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FDPS | P14324 | 7/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etidronic Acid SCHEMBL20292490 | 0.94 | LMNA (0.63) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL1515049 | 0.94 | LMNA (0.63) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL10957072 | 0.92 | LMNA (0.60) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL3897761 | 0.92 | LMNA (0.60) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL29631751 | 0.92 | LMNA (0.60) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL10957062 | 0.80 | LMNA (0.77) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL157065 | 0.79 | LMNA (0.47) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL11584272 | 0.79 | LMNA (0.47) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL8666317 | 0.79 | LMNA (0.47) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL6136322 | 0.79 | LMNA (0.47) | LMNAFDPSGGPS1PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194505-B1 | DRY PROCESS FOR PREPARING A SURFACE-MODIFIED ALKALINE EARTH METAL CARBONATE-CONTAINING MATERIAL | OMYA INT AG (CH) | 2022-03-02 | — | — | EP | disclosed |
| US-10836646-B2 | Dry process for preparing a surface-modified alkaline earth metal carbonate-containing material | OMYA INTERNATIONAL AG (US) | 2020-11-17 | — | — | US | disclosed |
| US-20170275175-A1 | DRY PROCESS FOR PREPARING A SURFACE-MODIFIED ALKALINE EARTH METAL CARBONATE-CONTAINING MATERIAL | OMYA INTERNATIONAL AG (CH) | 2017-09-28 | — | — | US | disclosed |
| EP-3194505-A1 | DRY PROCESS FOR PREPARING A SURFACE-MODIFIED ALKALINE EARTH METAL CARBONATE-CONTAINING MATERIAL | Omya International AG (CH) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016041781-A1 | DRY PROCESS FOR PREPARING A SURFACE-MODIFIED ALKALINE EARTH METAL CARBONATE-CONTAINING MATERIAL | OMYA INTERNATIONAL AG (CH) | 2016-03-24 | — | — | WO | disclosed |
| EP-2995654-A1 | Dry process for preparing a surface-modified alkaline earth metal carbonate-containing material | Omya International AG (CH) | 2016-03-16 | — | — | EP | disclosed |