⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973133 | 0.78 | — | — | |
| SCHEMBL29973217 | 0.77 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL18284840 | 0.66 | — | — | |
| SCHEMBL2472610 | 0.64 | — | — | |
| SCHEMBL29096350 | 0.61 | — | — | |
| Bromide SCHEMBL30537821 | 0.59 | NOS3 (0.31) | — | |
| SCHEMBL31474351 | 0.59 | — | — | |
| SCHEMBL28904639 | 0.58 | — | — | |
| SCHEMBL3816627 | 0.58 | — | — | |
| SCHEMBL28609118 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834248-B1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2016-03-16 | — | — | EP | disclosed |