Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829888 | 0.81 | HTT (0.53) | MAPK1KDM4ENPSR1HSD17B10KMT2A | |
| SCHEMBL8377547 | 0.80 | KMT2A (0.44) | MAPK1KDM4ENPSR1HSD17B10KMT2A | |
| SCHEMBL7825354 | 0.78 | HTT (0.46) | MAPK1KDM4ENPSR1HSD17B10KMT2A | |
| SCHEMBL1582221 | 0.72 | GRIN1 (0.44) | MAPK1GRIN1GRIN2AHTTPDE5A | |
| SCHEMBL17437974 | 0.72 | POLB (0.41) | GRIN1GRIN2AKMT2AALDH1A1GAA | |
| SCHEMBL27701766 | 0.72 | GRIN1 (0.34) | MAPK1KDM4ENPSR1HSD17B10GRIN1 | |
| SCHEMBL18131803 | 0.71 | GRIN1 (0.39) | HSD17B10GRIN1GRIN2AALDH1A1GAA | |
| SCHEMBL18131842 | 0.71 | GRIN1 (0.39) | GRIN1GRIN2AALDH1A1SMN1; SMN2PDE5A | |
| SCHEMBL27395034 | 0.71 | HTT (0.49) | MAPK1KDM4ENPSR1HSD17B10KMT2A | |
| SCHEMBL9753967 | 0.70 | PTGS1 (0.33) | KDM4EHSD17B10KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547678-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2016-03-16 | — | — | EP | disclosed |