Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605173 | 0.71 | P4HTM (0.36) | PTGS1PTGS2TDP1AKR1B1KDM4E | |
| Methyl Alcohol SCHEMBL9753918 | 0.69 | TBXAS1 (0.36) | PTGS1PTGS2TDP1AKR1B1KDM4E | |
| SCHEMBL8609867 | 0.68 | PTGS1 (0.47) | PTGS1PTGS2TDP1KDM4EALDH1A1 | |
| Methyl Alcohol SCHEMBL9753894 | 0.66 | PTGS1 (0.45) | PTGS1PTGS2TDP1KDM4EALDH1A1 | |
| SCHEMBL8606787 | 0.65 | GGPS1 (0.35) | PTGS1PTGS2TDP1AKR1B1KDM4E | |
| SCHEMBL8704239 | 0.65 | HDAC6 (0.37) | KDM4EALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9753964 | 0.64 | PTGS1 (0.34) | PTGS1PTGS2TDP1KDM4EALDH1A1 | |
| SCHEMBL3775955 | 0.64 | CDK8 (0.47) | PTGS1PTGS2TDP1CTDSP1AKR1B1 | |
| Methyl Alcohol SCHEMBL9753272 | 0.63 | KDM4E (0.35) | PTGS1PTGS2TDP1AKR1B1KDM4E | |
| Hydrochloric Acid SCHEMBL19510410 | 0.62 | CDK8 (0.46) | PTGS1PTGS2TDP1CTDSP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | claimed |