Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753414 | 0.91 | HTR2A (0.53) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3649140 | 0.86 | HTR2A (0.46) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3752021 | 0.84 | HTR2A (0.55) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580953 | 0.80 | HTR6 (0.59) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17581014 | 0.80 | HTR6 (0.59) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580655 | 0.80 | HTR2A (0.45) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL949542 | 0.79 | HTR2A (0.52) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17581022 | 0.77 | HTR2A (0.55) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL19327054 | 0.76 | HTR6 (0.68) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL19327070 | 0.76 | HTR6 (0.68) | HTR2AHTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185555-B1 | QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBVIE DEUTSCHLAND (DE) | 2016-03-16 | — | — | EP | claimed |