Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156155 | 0.83 | MEN1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL1538392 | 0.83 | MEN1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL157125 | 0.82 | MEN1 (0.39) | MEN1KMT2ACCR1CHRM2CHRM4 | |
| SCHEMBL968705 | 0.82 | MEN1 (0.39) | MEN1KMT2ACCR1CHRM2CHRM4 | |
| SCHEMBL157279 | 0.82 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL523968 | 0.82 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL156223 | 0.81 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL159477 | 0.81 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2811768 | 0.79 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNACHRNB2 | |
| SCHEMBL5925778 | 0.79 | TDP1 (0.37) | MEN1KMT2ACCR1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611788-A2 | NICOTINE COMPOUNDS AND ANALOGS THEREOF, SYNTHETIC METHODS OF MAKING COMPOUNDS, AND METHODS OF USE | University of Florida Research Foundation, Incorporated (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031220-A2 | NICOTINE COMPOUNDS AND ANALOGS THEREOF, SYNTHETIC METHODS OF MAKING COMPOUNDS, AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-03-08 | — | — | WO | disclosed |