Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157125 | 1.00 | MEN1 (0.39) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL1538392 | 0.87 | MEN1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL156155 | 0.87 | MEN1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL523968 | 0.86 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL157279 | 0.86 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2719213 | 0.85 | CYP3A4 (0.39) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL156223 | 0.84 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL159477 | 0.84 | MEN1 (0.36) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL2811768 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAEPHX1 | |
| SCHEMBL5925778 | 0.82 | TDP1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994443-B2 | Modified nicotinic compounds and related methods | SELECTA BIOSCIENCES, INC. (US) | 2018-06-12 | — | — | US | claimed |
| EP-2640190-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | Selecta Biosciences, Inc. (US) | 2013-09-25 | — | — | EP | claimed |
| WO-2012061717-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | SELECTA BIOSCIENCES, INC. (US) | 2012-05-10 | — | — | WO | claimed |
| JP-2006504654-A | — | — | 2006-02-09 | — | — | JP | claimed |
| EP-1523334-A2 | HAPTEN-CARRIER CONJUGATES AND USES THEREOF | Cytos Biotechnology AG (CH) | 2005-04-20 | — | — | EP | claimed |
| WO-2004009116-A2 | HAPTEN-CARRIER CONJUGATES COMPRISING VIRUS LIKE PARTICLES AND USES THEREOF | CYTOS BIOTECHNOLOGY AG (CH) | 2004-01-29 | — | — | WO | claimed |
| US-9994443-B2 | Modified nicotinic compounds and related methods | SELECTA BIOSCIENCES, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2346528-B1 | NICOTINE IMMUNONANOTHERAPEUTICS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-04-06 | — | — | EP | disclosed |
| US-8932595-B2 | Nicotine immunonanotherapeutics | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-01-13 | — | — | US | disclosed |
| US-8591905-B2 | Nicotine immunonanotherapeutics | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2640190-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | Selecta Biosciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| US-20130142821-A1 | Hapten-Carrier Conjugates and Uses Thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2013-06-06 | — | — | US | disclosed |
| EP-2313390-B1 | PROCESS FOR THE PREPARATION OF NICOTINE-BASED HAPTENS | NOVARTIS AG (CH) | 2012-09-19 | — | — | EP | disclosed |
| US-4261893-A | INTERMEDIATES IN SYNTHESIS OF CHEMILUMINESCENT-LABELED CONJUGATES USED IN IMMUNOASSAYS | MILES LABORATORIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4238395-A | INTERMEDIATE OF CHEMILUMINESCENT NAPHTHALENE-1,2-DICARBOXYLIC ACID HYDRAZIDE-LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4226993-A | INTERMEDIATES FOR CHEMILUMINESCENT LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226992-A | INTERMEDIATES FOR CHEMILUMINESCENT LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4225485-A | Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-labeled polypeptides and proteins | MILES LABORATORIES, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4213893-A | Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays | MILES LABORATORIES, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4212805-A | INTERMEDIATES OF PHTHALHYDRAZIDE-LABELED CONJUGATES | MILES LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |