Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.97 |
| ▸ | CASP6 | P55212 | 3/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819272 | 0.98 | SNCA (1.00) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL591962 | 0.98 | SNCA (1.00) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL29411849 | 0.98 | SNCA (1.00) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL42176 | 0.98 | SNCA (1.00) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL18425292 | 0.97 | SNCA (0.97) | SNCACASP6NSD2DUSP3PTPN5 | |
| Potassium SCHEMBL1758452 | 0.97 | SNCA (0.97) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL4349757 | 0.88 | SNCA (0.83) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL2762493 | 0.84 | SNCA (0.75) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL11773321 | 0.84 | SNCA (0.74) | SNCACASP6L3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL11511934 | 0.84 | CASP6 (0.78) | SNCACASP6NSD2DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056682-A1 | REVERSE HEAD GROUP LIPIDS, LIPID PARTICLE COMPOSITIONS COMPRISING REVERSE HEADGROUP LIPIDS, AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-05-12 | — | — | WO | disclosed |