Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879754 | 0.91 | CCR1 (0.52) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL27863436 | 0.88 | CCR1 (0.53) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL1758544 | 0.87 | CCR1 (0.53) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL8513975 | 0.85 | CCR1 (0.54) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL8513972 | 0.84 | CCR1 (0.52) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL2579871 | 0.83 | CCR1 (0.52) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL1120153 | 0.83 | GAA (0.48) | CCR1GAAKDM4ETP53L3MBTL1 | |
| SCHEMBL25757726 | 0.83 | CCR1 (0.51) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL1228604 | 0.82 | CCR1 (0.49) | CCR1GAAKDM4ECXCR3TP53 | |
| SCHEMBL28799628 | 0.81 | CCR1 (0.50) | CCR1GAAKDM4ECXCR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493886-B1 | HETEROARYL PIPERIDINE AND PIPERAZINE DERIVATES | BAYER CROPSCIENCE AG (DE) | 2014-11-26 | — | — | EP | disclosed |
| EP-2493886-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051244-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |