Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758544 | 0.91 | CCR1 (0.53) | CCR1GAAOGAKDM4ECXCR3 | |
| SCHEMBL8513975 | 0.88 | CCR1 (0.54) | CCR1GAAKDM4ECXCR3LMNA | |
| SCHEMBL25757907 | 0.88 | CCR1 (0.50) | CCR1GAAKDM4ECXCR3LMNA | |
| SCHEMBL2579871 | 0.88 | CCR1 (0.52) | CCR1GAAOGAKDM4ECXCR3 | |
| SCHEMBL25757726 | 0.84 | CCR1 (0.51) | CCR1GAAKDM4ECXCR3LMNA | |
| SCHEMBL1758546 | 0.84 | CCR1 (0.54) | CCR1GAAKDM4ECXCR3LMNA | |
| SCHEMBL1758419 | 0.83 | GAA (0.49) | CCR1GAASCDKDM4ECXCR3 | |
| SCHEMBL8512452 | 0.83 | GAA (0.49) | CCR1GAAKDM4ELMNATP53 | |
| SCHEMBL27863436 | 0.83 | CCR1 (0.53) | CCR1GAAKDM4ECXCR3LMNA | |
| SCHEMBL28799628 | 0.82 | CCR1 (0.50) | CCR1GAAKDM4ECXCR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643312-B1 | MICROBICIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-8748431-B2 | Microbicidal heterocycles | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-10 | — | — | US | disclosed |
| US-20130324544-A1 | MICROBICIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-05 | — | — | US | disclosed |
| US-8557821-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION, LLC (US) | 2013-10-15 | — | — | US | disclosed |
| EP-2643312-A1 | MICROBICIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2013-10-02 | — | — | EP | disclosed |
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
| WO-2012069633-A1 | MICROBICIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324544-A1 | MICROBICIDAL HETEROCYCLES | CYP1A1, CYP1B1, CYP51A1 | CCR1 249/4885GAA 684/4885SCD 2681/4885 |
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | MPO, CYP51A1, CYP1A1 | CCR1 487/4885GAA 560/4885SCD 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.