Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200911 | 0.90 | CYP1A2 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL27430931 | 0.89 | RAB9A (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL2385445 | 0.88 | CYP2D6 (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL5058711 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL31361960 | 0.84 | CYP2C9 (0.52) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL17586501 | 0.81 | RAB9A (0.67) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL30819141 | 0.80 | CYP2D6 (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL12253450 | 0.77 | — | — | |
| SCHEMBL10712742 | 0.74 | BRS3 (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL26762537 | 0.74 | BRS3 (0.52) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422534-B2 | Synthesis of prazole compounds | CODEXIS, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160076008-A1 | SYNTHESIS OF PRAZOLE COMPOUNDS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-03-17 | — | — | US | disclosed |