Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425396 | 0.78 | KDM4A (0.53) | KDM4ALMNAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1759196 | 0.78 | MEN1 (0.52) | EPHX2P2RX7NPC1RAB9AMEN1 | |
| SCHEMBL10525905 | 0.76 | CYSLTR2 (0.56) | MEN1KMT2ALMNAPTGS1 | |
| SCHEMBL8889150 | 0.72 | AKR1C3 (0.47) | KDM4ALMNAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1758576 | 0.72 | HDAC1 (0.51) | P2RX7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1574429 | 0.70 | AKR1C3 (0.58) | LMNAAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL28060952 | 0.69 | EPHX2 (0.57) | EPHX2P2RX7NPC1RAB9ASIGMAR1 | |
| SCHEMBL1758919 | 0.69 | HDAC6 (0.44) | EPHX2P2RX7MEN1KMT2ALMNA | |
| SCHEMBL1252344 | 0.69 | CYP2C9 (0.58) | MEN1KMT2ALMNAAKR1C3AKR1C2 | |
| SCHEMBL11457389 | 0.68 | PTGS1 (0.51) | KDM4ALMNAAKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |