Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056506 | 0.80 | MEN1 (0.59) | MEN1KMT2AALDH1A1P2RX7EPHX2 | |
| SCHEMBL1758576 | 0.79 | HDAC1 (0.51) | MEN1KMT2AP2RX7NPC1RAB9A | |
| SCHEMBL1758736 | 0.78 | EPHX2 (0.40) | MEN1KMT2AP2RX7NPC1RAB9A | |
| SCHEMBL371605 | 0.77 | RARB (0.71) | MEN1KMT2ARARBALDH1A1RARA | |
| SCHEMBL28060952 | 0.76 | EPHX2 (0.57) | MEN1KMT2AALDH1A1P2RX7NPC1 | |
| SCHEMBL19524619 | 0.75 | P2RX7 (0.49) | MEN1KMT2AALDH1A1P2RX7EPHX2 | |
| SCHEMBL9472454 | 0.75 | RARB (0.72) | MEN1KMT2ARARBALDH1A1RARA | |
| SCHEMBL30053056 | 0.75 | RARB (0.72) | MEN1KMT2ARARBALDH1A1RARA | |
| SCHEMBL15583704 | 0.75 | RARB (0.72) | MEN1KMT2ARARBALDH1A1RARA | |
| SCHEMBL28873230 | 0.75 | RARB (0.72) | MEN1KMT2ARARBALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |