SCHEMBL175880

SCHEMBL175880

COc1ccc(/C=C/c2ccccc2/C=C/c2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 15/20 0.89
CYP1A1 P04798 15/20 0.89
CYP1B1 Q16678 15/20 0.89
NFE2L2 Q16236 2/20 0.73
CYP3A4 P08684 2/20 0.69
CYP2C19 P33261 2/20 0.69
MEN1 O00255 2/20 0.69
ALDH1A1 P00352 2/20 0.69
MAPT P10636 2/20 0.69
KMT2A Q03164 2/20 0.69
CYP2E1 P05181 1/20 0.69
CYP2C8 P10632 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2A6 P11509 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP4B1 P13584 1/20 0.69
CYP2B6 P20813 1/20 0.69
CYP3A5 P20815 1/20 0.69
CYP2A7 P20853 1/20 0.69
CYP3A7 P24462 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175881 1.00 CYP1A2 (0.89) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL25706432 0.92 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL5498411 0.87 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL5498406 0.87 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL14401250 0.87 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL21030089 0.85 CYP1A1 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL26924044 0.84 CYP1A2 (0.84) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL30135261 0.84 CYP1A2 (1.00) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL13189258 0.83 CYP1A2 (0.73) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL13169393 0.83 CYP1A2 (0.73) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US claimed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-8304153-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, electrophotographic process cartridge RICOH COMPANY, LTD. (JP) 2012-11-06 US disclosed
US-8298734-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-10-30 US disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
US-4708921-A Photosensitive material containing disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1987-11-24 US disclosed
US-4702979-A ELECTROCONDUCTIVE CATHODE LAYER, PHOTOCONDUCTIVE LAYER OF CHARGE-GENERATING ORGANIC PIGMENT, ANODIC ION REACTION AT INTERFACE WHEN IRRADIATED RICOH CO., LTD. (JP) 1987-10-27 US disclosed
US-4672149-A PHOTOACTIVE LAYER CONTAINING A DISAZO PIGMENT; SOLAR CELLS; EFFICIENCY RICOH CO., LTD. (JP) 1987-06-09 US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4565759-A PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT RICOH CO., LTD. (JP) 1986-01-21 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR CYP1A2 135/4885CYP1A1 26/4885CYP1B1 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.