Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 15/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 15/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.73 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.73 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.73 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.73 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.73 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.73 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.73 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.73 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.73 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401250 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL5498406 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| Nitrogen SCHEMBL8500959 | 0.95 | CYP1A2 (0.91) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL2622576 | 0.92 | CYP1A2 (0.84) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL5495428 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL5495431 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL175880 | 0.87 | CYP1A2 (0.89) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL175881 | 0.87 | CYP1A2 (0.89) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL25706432 | 0.87 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4 | |
| SCHEMBL1067296 | 0.86 | CYP1A1 (0.76) | CYP1A2CYP1A1CYP1B1NFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-9101920-B2 | Palladium catalyst, method for its preparation and its use | H4SEP KFT (HU) | 2015-08-11 | — | — | US | disclosed |
| US-9056314-B2 | Palladium catalyst, method for its preparation and its use | H4SEP KFT (HU) | 2015-06-16 | — | — | US | disclosed |
| WO-2015085143-A2 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM (US) | 2015-06-11 | — | — | WO | disclosed |
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140012004-A1 | NEW PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | H4SEP KFT (HU) | 2014-01-09 | — | — | US | disclosed |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | CHINOIN GYOGYSZER-ES VEGYESZETI TER-MEKEK GYARA ZRT (HU) | 2013-10-24 | — | — | US | disclosed |
| EP-2651856-A1 | A NEW PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | H4 Sep Kft (HU) | 2013-10-23 | — | — | EP | disclosed |
| CN-103242167-A | Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge | RICOH CO LTD | 2013-08-14 | — | — | CN | disclosed |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | STC.UNM (US) | 2013-07-11 | — | — | US | disclosed |
| CN-101919830-B | Novel application of 2,4-dimethoxyl trans-stilbene | INST BASIC MED SCIENCES PLA | 2013-07-03 | — | — | CN | disclosed |
| WO-2012093271-A1 | A NEW PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | H4SEP KFT (HU) | 2012-07-12 | — | — | WO | disclosed |
| CN-101919830-A | Novel application of 2,4-dimethoxyl trans-stilben | INST BASIC MED SCIENCES PLA | 2010-12-22 | — | — | CN | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
| EP-1063264-B1 | Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus | RICOH KK (JP) | 2006-03-01 | — | — | EP | disclosed |
| CN-1058369-C | Pest control chemicals against pine wood nematodes | KIORITZ CORP (JP) | 2000-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | CYP1A2 1332/4885CYP1A1 1445/4885CYP1B1 1256/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | CYP1A2 1159/4885CYP1A1 874/4885CYP1B1 713/4885 |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | PDS5A, DDT, PDS5B | CYP1A2 1603/4885CYP1A1 1168/4885CYP1B1 1446/4885 |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | PSEN1, TERT, PSEN2 | CYP1A2 1201/4885CYP1A1 809/4885CYP1B1 936/4885 |
| US-20140012004-A1 | NEW PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | DDT, PDS5A, PDS5B | CYP1A2 2114/4885CYP1A1 1714/4885CYP1B1 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.