Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272571 | 0.70 | — | — | |
| SCHEMBL15241323 | 0.70 | — | — | |
| SCHEMBL14162629 | 0.68 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL14451325 | 0.66 | — | — | |
| SCHEMBL740847 | 0.66 | — | — | |
| SCHEMBL3052817 | 0.66 | — | — | |
| SCHEMBL5074460 | 0.66 | TDP1 (0.58) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL13327032 | 0.66 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| Hydrochloric Acid SCHEMBL5073886 | 0.65 | TDP1 (0.56) | RAB9ANPC1SMN1; SMN2PARP15PARP10 | |
| SCHEMBL5540669 | 0.64 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235008-B1 | AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-16 | — | — | EP | disclosed |