SCHEMBL17589221

SCHEMBL17589221

COc1ccc(-c2ccc(-c3ccc(Oc4ccc(S(=O)(=O)c5ccc(-c6ccc(S(=O)(=O)c7ccc(C)cc7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ PKM P14618 2/20 0.66
▸ TDP1 Q9NUW8 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ GAA P10253 2/20 0.56
▸ ALDH1A1 P00352 6/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ CYP2C19 P33261 1/20 0.55
▸ RAPGEF4 Q8WZA2 1/20 0.54
▸ ACHE P22303 2/20 0.53
▸ BCHE P06276 1/20 0.53
▸ KDM4E B2RXH2 2/20 0.51
▸ MAPT P10636 4/20 0.48
▸ TSHR P16473 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400743 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL686308 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL12449374 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13910302 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL685432 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL685435 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL17589219 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13817371 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL12014949 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13400752 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 — — US disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 — — US disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 — — US disclosed
US-20170022322-A1 New polymeric materials SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-01-26 — — US disclosed
US-20170022322-A1 New polymeric materials SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-01-26 — — US disclosed
WO-2016102277-A1 METHODS FOR MAKING POLYARYLENE ETHER SULFONE (PAES) POLYMERS WITH SILYLATED TERPHENYL COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-30 — — WO disclosed
US-20160168332-A1 Chemical processing article SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-16 — — US disclosed
US-20160168332-A1 Chemical processing article SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-16 — — US disclosed
US-20160159986-A1 Polyarylethersulfone Oil and Gas Recovery Articles, Method of Preparation and Method of Use SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-09 — — US disclosed
US-20160159986-A1 Polyarylethersulfone Oil and Gas Recovery Articles, Method of Preparation and Method of Use SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-09 — — US disclosed
WO-2016071088-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-05-12 — — WO disclosed
US-20160090450-A1 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-31 — — US disclosed
US-20160090450-A1 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-31 — — US disclosed
US-20160083523-A1 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-24 — — US disclosed
US-20160083523-A1 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-24 — — US disclosed
US-20160075876-A1 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-17 — — US disclosed
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