SCHEMBL12014949

SCHEMBL12014949

COc1ccc(S(=O)(=O)c2ccc(Oc3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ PKM P14618 2/20 0.66
▸ TDP1 Q9NUW8 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ GAA P10253 2/20 0.56
▸ ALDH1A1 P00352 6/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ CYP2C19 P33261 1/20 0.55
▸ RAPGEF4 Q8WZA2 1/20 0.54
▸ ACHE P22303 2/20 0.53
▸ BCHE P06276 1/20 0.53
▸ KDM4E B2RXH2 2/20 0.51
▸ MAPT P10636 4/20 0.48
▸ TSHR P16473 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400743 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL686308 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL12449374 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13910302 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL685432 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL685435 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL17589219 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13817371 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL17589221 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13400752 1.00 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226671-A9 GOLF CLUB HEAD TAYLOR MADE GOLF COMPANY, INC. 2024-07-11 — — US disclosed
US-12023558-B2 Golf club heads TAYLOR MADE GOLF COMPANY, INC. (US) 2024-07-02 — — US disclosed
US-12023558-B2 Golf club heads TAYLOR MADE GOLF COMPANY, INC. (US) 2024-07-02 — — US disclosed
US-20240024739-A1 GOLF CLUB HEADS TAYLOR MADE GOLF COMPANY, INC. (US) 2024-01-25 — — US disclosed
US-20240026083-A1 Bioactive compound immobilization on sulfone polymers SYENSQO SPECIALTY POLYMERS USA, LLC 2024-01-25 — — US disclosed
US-20240026156-A1 BORATE SALTS, POLYMERS AND COMPOSITES UCHICAGO ARGONNE, LLC (US) 2024-01-25 — — US disclosed
US-20240017135-A1 GOLF CLUB INCLUDING COMPOSITE MATERIAL WITH COLOR COATED FIBERS AND METHODS OF MAKING THE SAME TAYLOR MADE GOLF CO (US) 2024-01-18 — — US disclosed
US-20230381605-A1 MULTI-PIECE GOLF CLUB HEAD JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2023-11-30 — — US disclosed
US-20230381605-A1 MULTI-PIECE GOLF CLUB HEAD JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2023-11-30 — — US disclosed
US-20230374304-A1 THERMOPLASTIC POLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-11-23 — — US disclosed
US-20090212253-A1 POLYMER ELECTROLYTE COMPOSITION UBE INDUSTRIES, LTD. (JP) 2009-08-27 — — US disclosed
US-20090212253-A1 POLYMER ELECTROLYTE COMPOSITION UBE INDUSTRIES, LTD. (JP) 2009-08-27 — — US disclosed
US-7563850-B2 Aromatic polymer with either carbonyl and/or sulfone groups and cationic group for conductivity and anhydrous or solvent UBE INDUSTRIES, LTD. (JP) 2009-07-21 — — US disclosed
US-7563850-B2 Aromatic polymer with either carbonyl and/or sulfone groups and cationic group for conductivity and anhydrous or solvent UBE INDUSTRIES, LTD. (JP) 2009-07-21 — — US disclosed
US-20090124961-A1 Aerosol Valve BTG INTERNATIONAL LIMITED (GB) 2009-05-14 — — US disclosed
US-20090018242-A1 POLYETHERIMIDE/POLYPHENYLENE ETHER SULFONE BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2009-01-15 — — US disclosed
US-20090018265-A1 POLYETHERIMIDE/POLYPHENYLENE ETHER SULFONE BLENDS GENERAL ELECTRIC COMPANY (US) 2009-01-15 — — US disclosed
US-20080142418-A1 FUNCTIONAL POLYARYLETHERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 — — US disclosed
US-20080142429-A1 FUNCTIONAL POLYARYLETHERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 — — US disclosed
US-7258941-B2 Polymer electrolyte for solid polymer type fuel cell and fuel cell UBE INDUSTRIES, LTD. (JP) 2007-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240026156-A1 BORATE SALTS, POLYMERS AND COMPOSITES SLC26A3, SLC9A3, SLC9A1 HTT 2629/4885SMN1; SMN2 3135/4885PKM 2280/4885
US-20240026083-A1 Bioactive compound immobilization on sulfone polymers PLG, PHOSPHO1, FGB HTT 4239/4885SMN1; SMN2 3957/4885PKM 724/4885
US-20080142429-A1 FUNCTIONAL POLYARYLETHERS CBR3, NR2E3, HRH4 HTT 3514/4885SMN1; SMN2 4380/4885PKM 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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