Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 19/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17590539 | 1.00 | P2RX3 (0.62) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL17590673 | 0.93 | P2RX3 (0.62) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL17590350 | 0.91 | P2RX3 (0.60) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL19183841 | 0.91 | P2RX3 (0.60) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL10055436 | 0.91 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL17590352 | 0.91 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL10055992 | 0.88 | P2RX3 (0.60) | P2RX3 | |
| SCHEMBL19185137 | 0.87 | P2RX3 (0.55) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL19185041 | 0.87 | P2RX3 (0.53) | P2RX3ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL17590365 | 0.85 | P2RX3 (0.59) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| EP-2604595-B1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | SHIONOGI & CO (JP) | 2016-03-16 | — | — | EP | disclosed |