Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9977921 | 0.86 | CYP3A4 (0.51) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9977944 | 0.82 | CYP3A4 (0.51) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9977924 | 0.81 | CYP3A4 (0.49) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9978021 | 0.81 | CYP3A4 (0.50) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9977920 | 0.81 | CYP3A4 (0.51) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9978047 | 0.81 | CYP3A4 (0.49) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL15293737 | 0.80 | CYP3A4 (0.54) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9977943 | 0.80 | CYP3A4 (0.58) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9977960 | 0.78 | CYP3A4 (0.66) | CYP3A4OPRM1OPRL1TNKS | |
| SCHEMBL9978113 | 0.78 | CYP3A4 (0.64) | CYP3A4OPRM1OPRL1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651933-B1 | AZABENZIMIDAZOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-16 | — | — | EP | disclosed |