SCHEMBL9977924

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9977920	0.91	CYP3A4 (0.51)	CYP3A4CNR2OPRL1ALDH1A1OPRM1
	SCHEMBL9977921	0.85	CYP3A4 (0.51)	CYP3A4OPRL1ALDH1A1OPRM1TNKS
	SCHEMBL9978021	0.84	CYP3A4 (0.50)	CYP3A4OPRL1OPRM1TNKSCYP2D6
	SCHEMBL9978047	0.83	CYP3A4 (0.49)	CYP3A4OPRL1OPRM1TNKSCYP2D6
	SCHEMBL9977943	0.83	CYP3A4 (0.58)	CYP3A4OPRL1ALDH1A1TSHROPRM1
	SCHEMBL15293737	0.83	CYP3A4 (0.54)	CYP3A4OPRL1ALDH1A1TSHROPRM1
	SCHEMBL17591111	0.81	CYP3A4 (0.45)	CYP3A4OPRL1OPRM1TNKS
	SCHEMBL9977960	0.81	CYP3A4 (0.66)	CYP3A4OPRL1ALDH1A1TSHROPRM1
	SCHEMBL9977922	0.80	CYP3A4 (0.46)	CYP3A4OPRL1OPRM1TNKSCYP2D6
	SCHEMBL15282842	0.76	CYP3A4 (0.45)	CYP3A4OPRL1TSHROPRM1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.