Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.63 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | CCKAR | P32238 | 5/20 | 0.41 |
| ▸ | CCKBR | P32239 | 5/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558792 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4561886 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4541595 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4535900 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL15633597 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL2181197 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4539094 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4004880 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4543138 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 | |
| SCHEMBL4540624 | 1.00 | GLP1R (0.63) | GLP1RNOD1CCKARCCKBRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040660-B2 | Long-acting gastrin derivatives | NOVO NORDISK A/S (DK) | 2015-05-26 | — | — | US | claimed |
| US-20130096055-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2013-04-18 | — | — | US | claimed |
| US-20130059781-A1 | Long-Acting Gastrin Derivatives | NOVO NORDISK A/S (DK) | 2013-03-07 | — | — | US | claimed |
| EP-2057189-B1 | ACYLATED EXENDIN-4 COMPOUNDS | NOVO NORDISK AS (DK) | 2013-03-06 | — | — | EP | claimed |
| EP-2560675-A1 | LONG-ACTING GASTRIN DERIVATIVES | Novo Nordisk A/S (DK) | 2013-02-27 | — | — | EP | claimed |
| US-20130040877-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2013-02-14 | — | — | US | claimed |
| EP-2498800-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | Novo Nordisk A/S (DK) | 2012-09-19 | — | — | EP | claimed |
| EP-2477643-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | Novo Nordisk A/S (DK) | 2012-07-25 | — | — | EP | claimed |
| WO-2011131646-A1 | LONG-ACTING GASTRIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2011-10-27 | — | — | WO | claimed |
| WO-2011058165-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2011-05-19 | — | — | WO | claimed |
| WO-2011033068-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2011-03-24 | — | — | WO | claimed |
| US-9657079-B2 | Truncated GLP-1 derivatives and their therapeutical use | NOVO NORDISK A/S (DK) | 2017-05-23 | — | — | US | disclosed |
| EP-2190873-B1 | TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK AS (DK) | 2015-07-22 | — | — | EP | disclosed |
| US-9040660-B2 | Long-acting gastrin derivatives | NOVO NORDISK A/S (DK) | 2015-05-26 | — | — | US | disclosed |
| US-20140296131-A1 | Truncated GLP-1 Derivatives and Their Therapeutical Use | NOVO NORDISK A/S (DK) | 2014-10-02 | — | — | US | disclosed |
| WO-2011051312-A1 | DERIVATIVES OF CGRP | NOVO NORDISK A/S (DK) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011033068-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2011-03-24 | — | — | WO | disclosed |
| US-20100292133-A1 | TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| EP-2190873-A1 | TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE | Novo Nordisk A/S (DK) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009030774-A1 | TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096055-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NPY2R, NPY1R, NPY5R | GLP1R 5/4885NOD1 3136/4885CCKAR 34/4885 |
| US-20100292133-A1 | TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE | GLP1R, GIPR, IAPP | GLP1R 1/4885NOD1 295/4885CCKAR 121/4885 |
| US-20130059781-A1 | Long-Acting Gastrin Derivatives | GIPR, GRPR, CCKBR | GLP1R 4/4885NOD1 3848/4885CCKAR 12/4885 |
| US-20130040877-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NPY2R, NPY1R, NPY5R | GLP1R 5/4885NOD1 2388/4885CCKAR 45/4885 |
| US-20140296131-A1 | Truncated GLP-1 Derivatives and Their Therapeutical Use | GLP1R, GIPR, IAPP | GLP1R 1/4885NOD1 422/4885CCKAR 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.