Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759295 | 0.86 | FEN1 (0.42) | PTGER1PTGER4PTGER3PTGER2MAOA | |
| SCHEMBL1758960 | 0.85 | PTGER4 (0.44) | PTGER1PTGER4PTGER3PTGER2GSTP1 | |
| SCHEMBL1638769 | 0.79 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2GSTP1 | |
| SCHEMBL18495742 | 0.78 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL1638061 | 0.76 | MAOB (0.62) | PTGER1PTGER4PTGER3PTGER2MAOA | |
| SCHEMBL1420024 | 0.75 | AGXT (0.52) | MAOA | |
| SCHEMBL6640539 | 0.74 | MAPT (0.55) | PTGER1PTGER4PTGER3PTGER2GSTP1 | |
| SCHEMBL1009475 | 0.74 | MAOB (0.68) | MAOAMAOBFFAR1CCNB2CDK1 | |
| SCHEMBL27877418 | 0.74 | HPGD (0.50) | PTGER1PTGER4PTGER3PTGER2GSTP1 | |
| SCHEMBL12727690 | 0.73 | HTR1A (0.49) | PTGER1PTGER4PTGER3PTGER2GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493932-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056423-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |